𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Unraveling the Mysteries of IGF-1 Signaling in Melanoma

✍ Scribed by Lee, John T; Brafford, Patricia; Herlyn, Meenhard

Book ID
109875128
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
278 KB
Volume
128
Category
Article
ISSN
0022-202X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Role of PI3K/Akt signaling in insulin-li
Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion
✍ Erik Wilker; Jerry Lu; Okkyung Rho; Steve Carbajal; Linda BeltrΓ‘n; John DiGiovan πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 184 KB

## Abstract Overexpression of human IGF‐1 with the bovine keratin 5 (BK5) promoter (BK5.IGF‐1 transgenic mice) induces persistent epidermal hyperplasia and leads to spontaneous skin tumor formation. In previous work, PI3K and Akt activities were found to be elevated in the epidermis of BK5.IGF‐1 tr

Dual regulation of upstream binding fact
Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling
✍ Hongzhi Sun; Xiao Tu; Mingli Liu; Renato Baserga πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 357 KB

## Abstract The Upstream Binding Factor 1 (UBF1) is a nucleolar protein that participates in the regulation of RNA polymerase I activity and ribosomal RNA (rRNA) synthesis. In 32D myeloid cells expressing the type 1 insulin‐like growth factor receptor (IGF‐IR), the UBF1 protein (but not its mRNA) i