Asymmetric alkylation reaction of ฮฑ-fluo
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Shigeru Arai; Makoto Oku; Toshimasa Ishida; Takayuki Shioiri
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Article
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1999
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Elsevier Science
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French
โ 267 KB
The catalytic asymmetric alkylation reaction of 0t-fluorotetralones promoted by a chiral quaternary ammonium salt derived from cinchonine under phase-transfer catalyzed conditions was described. The reaction proceeded smoothly to give the desired products with up to 91% ee. This methodology provides