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Unnatural Rigid Scaffolds Targeting the Bacterial Ribosome

✍ Scribed by Ioannis A. Katsoulis; Constantina Pyrkotis; Athanasios Papakyriakou; Georgia Kythreoti; Alexandros L. Zografos; Ioannis Mavridis; Victoria R. Nahmias; Panoula Anastasopoulou; Dionisios Vourloumis


Book ID
102791245
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
602 KB
Volume
10
Category
Article
ISSN
1439-4227

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πŸ“œ SIMILAR VOLUMES


Second generation analogs of rigid 6,7-s
✍ Christos I. Stathakis; Ioannis Mavridis; Georgia Kythreoti; Athanasios Papakyria πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 695 KB

Previous work from our group described the synthesis and biological evaluation of new rigid, 6,6- and 6,7-spiro aminoglycosidic scaffolds targeting the bacterial ribosome. Herein we describe an improved synthetic protocol for their construction, and extend our study by further amino-functionalizatio