Uniformity of distribution of cyanocobalamin in tablet formulations

✍ Scribed by R. J. Nessel; H. M. Apelian; J. Blodinger

• Publisher: John Wiley and Sons
• Year: 1970
• Tongue: English
• Weight: 423 KB
• Volume: 59
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600590224

✦ Synopsis

Some of the distribution characteristics of three commercially available, protected cyanocobalamin forms were demonstrated in each of two vitamin formulations of dissimilar particle size. The incorporation of 57co cyanocobalamin into each of these protected forms permitted rapid, precise measurements of the distribution on individual unit doses. Statistical analysis of the data confirmed the visual observations of improved distribution of the 1 % gelatin product. Keyphrases 0 Cyanocobalamin-57Co-formulation distribution 0 Distribution characteristics-cyanocobalamin-57Co in tablets 0 Wet granulation, direct compression-cyanocobalamin-57Co distribution comparison 0 Scintillometry-analysis