Stability of cyanocobalamin in film-coated multivitamin tablets
β Scribed by James T. Jacob; Robert J. Nessel; Jack Blodinger
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 358 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
Some of the distribution characteristics of three commercially available, protected cyanocobalamin forms were demonstrated in each of two vitamin formulations of dissimilar particle size. The incorporation of 57co cyanocobalamin into each of these protected forms permitted rapid, precise measurement
The enteric film coating of placebo tablets, using a methacrylic acid-methyl methacrylate copolymer as the film former in the coating solution, was studied by statistical techniques. The effects of four independent formulation and process variables on the disintegration time of the coated film in si
Solvent-free formulations suitable for use as film coatings are described. Coatings are applied by spraying molten mixtures onto tablcts in a conventional coating pan. The ewects of a series of 17 additives on two representative basic formulations are evaluated. Results are presented relative to app