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Unexpected growth-stimulatory effect of somatostatin analogue on cultured human pancreatic carcinoid cells

✍ Scribed by Jin Ishizuka; R.Daniel Beauchamp; B.Mark Evers; Courtney M. Townsend Jr.; James C. Thompson


Book ID
115765477
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
325 KB
Volume
185
Category
Article
ISSN
0006-291X

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5-hydroxytryptamine (5-HT) is a mitogen for fibroblasts, vascular smooth muscle cells, renal mesangial cells, and jejunal crypt cells. The human carcinoid cell line (termed BON) that we established in our laboratory from a pancreatic carcinoid tumor produces and secretes 5-HT. In this study, therefo