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Effect of 5-HT3 receptor antagonist (ondansetron) on functioning human pancreatic carcinoid cells

✍ Scribed by J. Ishizuka; A.C. Hsieh; C.M. Townsend Jr; J.C. Thompson


Book ID
113404101
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
409 KB
Volume
2
Category
Article
ISSN
0960-7404

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5-hydroxytryptamine (5-HT) is a mitogen for fibroblasts, vascular smooth muscle cells, renal mesangial cells, and jejunal crypt cells. The human carcinoid cell line (termed BON) that we established in our laboratory from a pancreatic carcinoid tumor produces and secretes 5-HT. In this study, therefo