Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson's Disease
β Scribed by Kish, Stephen J.; Shannak, Kathleen; Hornykiewicz, Oleh
- Book ID
- 115504907
- Publisher
- Massachusetts Medical Society
- Year
- 1988
- Tongue
- English
- Weight
- 850 KB
- Volume
- 318
- Category
- Article
- ISSN
- 0096-6762
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π SIMILAR VOLUMES
Single voxel proton MRS was used to study brain metabolism in the striatum of patients diagnosed with idiopathic Parkinson's disease (PD). Peak metabolite ratios in long echo time spectra were evaluated in 151 patient spectra and 97 age-matched control spectra collected at four participating institu
## Abstract Striatal dopamine D~2~ receptor binding was studied in vivo with positron emission tomography in seven patients with early Parkinson's disease using [^11^C]βraclopride. The patients had unilateral symptoms and none of them had received levodopa treatment. The accumulation of [^11^C]βrac