Unequivocal distinction between betamethasone and dexamethasone by mass spectrometry
β Scribed by B. A. Lodge; P. Toft
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 203 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3549
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β¦ Synopsis
Unequivocal Distinction between Betamethasone and Dexamethasone by Mass Spectrometry
Keyphrases 0 Dexarnethasone, betarnethasonedistinction, determination c] Mass spectrometry-identity 1 Masssp,ectra were recorded on a Hitachi-Perkin-Elmer model RMU-6D with an ionization voltage of 70ev. The compounds were introduced 1'4-dien-3'20-dione) and dexamethasone (9a'fluoro-11 0, 17a,2 Itrihydroxy -16amethylpregna -1,4dien-directIy into the ioll chamber.
π SIMILAR VOLUMES
## Abstract Betamethasone and dexamethasone are two corticosteroids differing in the stereoisomery of their Cβ16 methyl group. These two compounds are imperfectly separated by reversedβphase liquid chromatography and their mass spectra are very similar, leading to a difficult unambiguous identifica
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