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Understanding the pathogenesis of primary peritoneal carcinoma: Involvement of the BRCA1 and p53 genes

โœ Scribed by John O Schorge; Samuel C Mok


Book ID
117253712
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
233 KB
Volume
30
Category
Article
ISSN
1532-8392

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## Abstract Germline mutations in the BRCA1 and BRCA2 genes are associated with a significantly increased lifetime risk for developing breast and/or ovarian cancer. However, incomplete penetrance and substantial variability in age of disease onset among carriers of the same mutation suggests the in