‘Understanding the genetic predisposition to anorexia nervosa’

✍ Scribed by David A. Collier; Pak C. Sham; Maria J. Arranz; Xun Hu; Janet Treasure

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 67 KB
• Volume: 7
• Category: Article
• ISSN: 1072-4133
• DOI: 10.1002/(sici)1099-0968(199905)7:2<96::aid-erv287>3.0.co;2-g

✦ Synopsis

Allele-wise:

Anorexia nervosa versus all controls: w 2 5.15, 1 df, p 0.023 [0.046] or 1.52 (95%CI 1.04±2.21). Anorexia nervosa versus female controls: w 2 3.23, 1 df, p 0.07 [0.14] or 1.48 (95%CI 0.96±2.28).

Genotype-wise:

Anorexia nervosa versus all controls: w 2 9.68, 2 df, p 0.008 [0.016]. Anorexia nervosa versus female controls: w 2 9.21, 2 df, p 0.01 [0.02].

Recessive model:

Anorexia nervosa versus all controls: w 2 9.61, 2 df, p 0.002 [0.004] or 2.52 (95%CI 1.33±4.77). Anorexia nervosa versus female controls: w 2 8.48, 2 df, p 0.004 [0.008] or 3.13 (95%CI 1.34±7.42). We suggest that p values be corrected for multiple testing by a factor of two, and the resulting values are shown in square brackets.