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Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib

✍ Scribed by Henk J. Broxterman; Kristy J. Gotink; Henk M.W. Verheul


Book ID
116413304
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
433 KB
Volume
12
Category
Article
ISSN
1368-7646

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## Abstract Overexpression of the P‐glycoprotein/multidrug resistance 1 __(MDR1)__ and multidrug resistance protein 1 __(MRP1)__ gene is closely associated with the clinical outcome of various malignancies, and it is involved in responses to some anticancer chemotherapeutic agents including doxorub