𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Uncapping NF-κB activity in pancreatic cancer

✍ Scribed by Gurumurthy, Sushma (author);Bardeesy, Nabeel (author)

Book ID
109849926
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
91 KB
Volume
30
Category
Article
ISSN
0261-4189

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mitogenic and antiapoptotic role of cons
Mitogenic and antiapoptotic role of constitutive NF-κB/Rel activity in pancreatic cancer
✍ Susanne Liptay; Christoph K. Weber; Leopold Ludwig; Martin Wagner; Guido Adler; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 769 KB

## Abstract The transcription factor NF‐κB/Rel was found to be constitutively activated in human pancreatic cancer. RelA is present in the nucleus in primary human pancreatic cancer samples as well as in pancreatic cancer cell lines. NF‐κB/Rel–binding activity consists of NF‐κB1(p50) and RelA(p65).

NF-κB activity blockade impairs the angi
NF-κB activity blockade impairs the angiogenic potential of human pancreatic cancer cells
✍ Henry Q. Xiong; James L. Abbruzzese; Edward Lin; Liwei Wang; Leizhen Zheng; Kepi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 326 KB

## Abstract The effect of blockade of NF‐κB activity on human pancreatic cancer angiogenesis was determined in an orthotopic xenograft model. Highly metastatic L3.3 human pancreatic cancer cells, which expressed an elevated level of constitutive NF‐κB activity, were transfected with a mutated IκBα

NF-κB activation in human prostate cance
NF-κB activation in human prostate cancer: Important mediator or epiphenomenon?
✍ Junghan Suh; Arnold B. Rabson 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 287 KB

## Abstract The NF‐κB family of transcription factors has been shown to be constitutively activated in various human malignancies, including leukemias, lymphomas, and a number of solid tumors. NF‐κB is hypothesized to contribute to development and/or progression of malignancy by regulating the expr