✦ LIBER ✦

Unbiased Estimation of Odds Ratio by Using Negative Binomial Plans

✍ Scribed by Charles Dewitt Roberts

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 293 KB
Volume: 35
Category: Article
ISSN: 0323-3847
DOI: 10.1002/bimj.4710350507

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✦ Synopsis

Abstract

The use of the negative binomial distribution in both the numerator and denominator in prospective studies leads to an unbiased estimate of the odds ratio and an exact expression for its variance. Sample sizes that minimize the variance of odds ratio estimates are specified. The variance of the odds ratio estimate is shown to be close to the Cramér‐Rao lower bound.

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✍ Dr. Ch. Roberts 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 252 KB 👁 2 views

The use of the binomial distribution for the numerator and the negative binomial for the denominator in prospective studies leads to an unbiased estimate of relative risk and an unbiased estimate for combining experiments. Optimal sample sizes for groups are calculated and confidence intervals for t