Fibrillar granules (FGs) represent neutrophilic primary granules containing clustered filaments. We investigated neutrophils in the bone marrow obtained from 17 patients with chronic myeloproliferative disorders (CMPD) by electron microscopy. FG-positive neutrophils were seen in 15 of the 17 CMPDs w
Ultrastructure of neutrophilic phagosome of autologous platelet in vivo in specific granule deficiency
β Scribed by Dr. Tohru Sakura; Hirokazu Murakami; Takafumi Matsushima; Jun'Ichi Tamura; Morio Sawamura; Jun Tsuchiya
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 333 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0361-8609
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β¦ Synopsis
The ultrastructure of neutrophilic phagosomes containing autologous platelets in vivo from a woman with specific granule deficiency is described. This phagosome formation was observed only when she had developed pneumonia due to Staphylococcus aureus. Therefore, the phenomenon might be induced by severe bacterial infection under an abnormal neutrophilic condition accompanied by specific granule deficiency.
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