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Ultrastructure of fibrillar granules in human neutrophils

✍ Scribed by Nobuo Takemori; Katsuyuki Hirai; Ryuichi Onodera; Nagahito Saito; Naoyuki Miyokawa

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
807 KB
Volume
47
Category
Article
ISSN
0361-8609

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✦ Synopsis

Fibrillar granules (FGs) represent neutrophilic primary granules containing clustered filaments. We investigated neutrophils in the bone marrow obtained from 17 patients with chronic myeloproliferative disorders (CMPD) by electron microscopy. FG-positive neutrophils were seen in 15 of the 17 CMPDs with varying frequencies. The diameter of FGfilaments was 7-8 nm, showing that they corresponded to neither intermediate filaments nor actin filaments.

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