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U-937 monocyte-mediated c-Jun dephosphorylation and AP-1 activation in human endometrial stromal cells

โœ Scribed by Ziming Yu; Dinesh M. Shah


Book ID
116433839
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
214 KB
Volume
116
Category
Article
ISSN
0301-2115

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Human monocytic leukemia U937 cells undergo apoptosis when treated with antitumor drugs, such as etoposide, camptothecin and mitomycin C. The molecular mechanism of the drug-induced apoptosis is not well understood. In this study, we found that 2-deoxyglucose (2DG), an analog of D-glucose and an ind