Type synthesis of 2T2R, 1T2R and 2R parallel mechanisms
β Scribed by Caixia Fan; Hongzhao Liu; Yanbin Zhang
- Book ID
- 119323819
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 283 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0094-114X
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Addition of diethyl phosphite to 2,3-O-cyclohexylidene-D-glyceraldehyde catalyzed by triethylamine or fluorides led to ca. 35:65 mixtures of diethyl (IR,2R)-and (1S,2R)-2,3-O-cyclohexylidene-l,2,3trihydroxypropylphosphonates (4a) and (4b). Application of lithium diethylphosphonate only slightly impr
A straightforward three step route to (1S,2R)-and (1R,2R)-[2H]-glycerols la and lb is reported. The key asymmetric step involves an AD-mix-l~ dihydroxylation on deuterium labelled Z-and E-allyl benzoates 4a and 4b. The route should facilitate the use of [2H]-glycerols la-ld in high enantiomeric puri