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Type of prion protein in UK farmers with Creutzfeldt-Jakob disease

✍ Scribed by Andrew F Hill; Robert G Will; James Ironside; John Collinge

Book ID
119503423
Publisher
The Lancet
Year
1997
Tongue
English
Weight
132 KB
Volume
350
Category
Article
ISSN
0140-6736

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Polymorphisms of the prion protein gene
Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease
✍ Mirella Salvatore; Maurizio Genuardi; Rosella Petraroli; Carlo Masullo; Marco D' πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 593 KB

Creutzfeldt-Jakob disease (CJD) is a transmissible neurodegenerative disorder characterized by the accumulation of the amyloid protein PrP in the CNS. Two coding polymorphisms of the PrP gene (PRNP) are a methionine (Met) to valine (Val) change at codon 129, and a deletion in the octapeptide coding