Polymorphisms of the prion protein gene
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Mirella Salvatore; Maurizio Genuardi; Rosella Petraroli; Carlo Masullo; Marco D'
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Article
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1994
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Springer
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English
β 593 KB
Creutzfeldt-Jakob disease (CJD) is a transmissible neurodegenerative disorder characterized by the accumulation of the amyloid protein PrP in the CNS. Two coding polymorphisms of the PrP gene (PRNP) are a methionine (Met) to valine (Val) change at codon 129, and a deletion in the octapeptide coding