Type C virus activation in “nontransformed” mouse cells by UV-irradiated herpes simplex virus
✍ Scribed by Berge Hampar; Masakazu Hatanaka; Gurmit Aulakh; Jeffrey G. Derge; Leo Lee; Stephen Showalter
- Book ID
- 119009480
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 516 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0042-6822
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## Abstract Infection of Kirsten sarcoma virus‐transformed non‐producer BALB‐3T3 mouse cells with UV‐irradiated mouse cytomegalovirus (MCMV) resulted in activation of a xenotropic type C virus detected by infectious center formation in permissive rat or mink cells. The levels of type C virus activa
## Abstract A transformed mouse cell line (H238) was obtained following the infection of 238 mouse cells with ultraviolet (UV) irradiation‐inactivated herpes simplex virus type 2 (HSV‐2). The transformed cells produced tumors with a 100% incidence within 8 weeks in 6‐week‐old syngeneic BALB/c mice