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Type 1 T-helper cell predominance in granulomas of Crohn’s disease

✍ Scribed by Tomomasa Kakazu; Junichi Hara; Takayuki Matsumoto; Shiro Nakamura; Nobuhide Oshitani; Tetsuo Arakawa; Atsuo Kitano; Kazuki Nakatani; Fukunori Kinjo; Tetsuo Kuroki


Book ID
119396407
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
383 KB
Volume
94
Category
Article
ISSN
0002-9270

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Various characteristics of atopic allergic disorders seem to be causally related with the activation of allergen-specific T helper lymphocytes with a type 2 cytokine secretion profile, including high levels of interleukin-4 and interleukin-5. These cytokines are responsible for the occurrence of ele