✦ LIBER ✦

Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate

✍ Scribed by Stanley Cohen; Grant W. Cannon; Michael Schiff; Arthur Weaver; Robert Fox; Nancy Olsen; Daniel Furst; John Sharp; Larry Moreland; Jacques Caldwell; Jeffrey Kaine; Vibeke Strand

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 93 KB
Volume: 44
Category: Article
ISSN: 0004-3591
DOI: 10.1002/1529-0131(200109)44:9<1984::aid-art346>3.0.co;2-b

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics, safety, and efficacy o

Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis

✍ Michael E. Weinblatt; Joel M. Kremer; Jonathan S. Coblyn; Agnes L. Maier; Simon 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB 👁 2 views

Treatment of early seropositive rheumato

Treatment of early seropositive rheumatoid arthritis with minocycline: Four-year followup of a double-blind, placebo-controlled trial

✍ James R. O'Dell; Gail Paulsen; Claire E. Haire; Kent Blakely; William Palmer; St 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB 👁 1 views

Objective. Rheumatoid arthritis (RA) causes substantial morbidity and mortality, and current treatments are suboptimal. Recent studies have demonstrated the short-term efficacy of minocycline in the treatment of patients with early RA. This study was undertaken to compare patients treated with conve

Function and health-related quality of l

Function and health-related quality of life: Results from a randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis

✍ Vibeke Strand; Peter Tugwell; Claire Bombardier; Andreas Maetzel; Bruce Crawford 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

Inhibition of neutrophil migration soon

Inhibition of neutrophil migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: Findings in a prospective, randomized, double-blind clinical trial in fifteen patients

✍ Maarten C. Kraan; Ben M. De Koster; Jan G. R. Elferink; Wendy J. Post; Ferdinand 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 1 views

Leflunomide is a novel immunomodulating drug that has recently been approved as a disease-modifying antirheumatic drug for the treatment of rheumatoid arthritis (RA). The aim of this study was to determine the relationship between the clinical effects of leflunomide and neutrophil migration. Method

Treatment of poor-prognosis early rheuma

Treatment of poor-prognosis early rheumatoid arthritis: A randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone

✍ S. M. Proudman; P. G. Conaghan; C. Richardson; B. Griffiths; M. J. Green; D. McG 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB 👁 1 views

Clinical improvement as reflected in mea

Clinical improvement as reflected in measures of function and health-related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis: Sensitivity and relative efficiency to detect a treatment effect in a twelve-month, placebo-controlled trial

✍ Peter Tugwell; George Wells; Vibeke Strand; Andreas Maetzel; Claire Bombardier; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB 👁 2 views