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Two Unusual Xanthones from the Bark of Garcinia xanthochymus

✍ Scribed by Yu Chen; Hua Fan; Guang-Zhong Yang; Yan Jiang; Fang-Fang Zhong; Hong-Wu He

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
187 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A new xanthone derivative, garcinexanthone F (1), which was found to possess an α,β‐unsaturated γ‐lactone moiety, and a new bisxanthone, bigarcinenone B (2), with a terpene bridge providing the xanthonexanthone linkage, were isolated from the bark of Garcinia xanthochymus. Their structures were elucidated by spectroscopic methods, especially 2D‐NMR techniques. The antioxidant assay in vitro showed that compounds 1 and 2 exhibited significant scavenging activities against 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical with IC~50~ values of 22.32 and 20.14 μM, and against HO^.^ radical with IC~50~ values of 1.16 and 2.85 μM, respectively.

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