Small dipeptide-based HIV protease inhib
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Yoshiaki Kiso; Hikaru Matsumoto; Sota Mizumoto; Tooru Kimura; Yoichi Fujiwara; K
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Article
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1999
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Wiley (John Wiley & Sons)
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English
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The human immunodeficiency virus (HIV) codes for an aspartic protease known to be essential for retroviral maturation and replication. HIV protease is formed from two identical 99 amino acid peptides. We synthesized [(NHCH 2 CH 2 -S-CH 2 CO) [51][52] , Ala 67,95 ]HIV-1 protease using the thioether c