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Two novel variants in the DOPA decarboxylase gene: association with bipolar affective disorder

✍ Scribed by Børglum, A D; Bruun, T G; Kjeldsen, T E; Ewald, H; Mors, O; Kirov, G; Russ, C; Freeman, B; Collier, D A; Kruse, T A

Book ID
110059058
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
185 KB
Volume
4
Category
Article
ISSN
1359-4184

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Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of 5-hydroxytryptamine (5-HT). An association study in bipolar affective disorder I or unipolar major affective disorder was performed by using a Bfa I restriction site polymorphism within intron 7 of the tryptophan hydroxylas