A novel mutation in the Ξ²-protein coding
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Milagros BalbΓn; Magnus Abrahamson; Lars Gustafson; Karin Nilsson; Arne Brun; An
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Article
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1992
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Springer
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English
β 329 KB
A novel mutation, a C to T transition at base pair 2124 in exon 17 of the amyloid beta-protein precursor (APP) gene, has been identified by direct sequencing of amplified DNA from two Alzheimer's disease (AD) patients. A simple oligonucleotide-hybridization procedure was developed to allow populatio