## Cutting Cystic fibrosis (CF) mutations have been identified in Slovenian CF patients using single-stranded conformation polymorphism (SSCP) analysis. The entire coding region and all of the splice junction sites were screened in 24 patients. By varying the electrophoretic conditions and composi
Two new mutations detected by single-strand conformation polymorphism analysis in cystic fibrosis from Russia
β Scribed by Tatanya E. Ivaschenko; Vladislav S. Baranov; Michael Dean
- Book ID
- 111703813
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 307 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Summary Singleβstranded conformation polymorphism (SSCP) analysis was used to examine the mutations of the chloroplast 16S rRNA locus of streptomycinβresistant mutants in __Nicotiana plumbaginifolia.__ DNA fragments of 121, 517, 968 and 1578 bp, each possessing a known point mutation, were gener
To detect mutations in the thiopurine S-methyltransferase gene (TPMT), we have developed a strategy based on single-strand conformation polymorphism (SSCP) analysis of the gene amplified by polymerase chain reaction (PCR). The sensitivity of the method was first evaluated by analyzing DNA samples fr
## Detection of mutations and polymorphisms in the p53 tumor suppressor gene by single-strand conformation polymorphism analysis Deciphering the genetic mechanisms in cancer development requires analysis of a large number of tumors for consistent genetic alterations. Single-strand conformational p