Two New Iridoid Alkaloids, Daphmacropodosidines A and B, from Daphniphyllum macropodum
✍ Scribed by Ning-Chuan Kong; Hong-Ping He; Yue-Hu Wang; Suo Gao; Yun-Tong Di; Xiao-Jiang Hao
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- German
- Weight
- 78 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Two new iridoid alkaloids, daphmacropodosidines A (1) and B (2), together with two known ones, daphcalycinosidine B and caldaphnidine F, were isolated from the fruits of Daphniphyllum maropodum. Their structures were established by spectral methods, especially 2D NMR spectra (^1^H,^1^H‐COSY, HMQC, HMBC, and NOESY), as well as chemical means.
📜 SIMILAR VOLUMES
## Abstract Two new daphniphyllum alkaloids named 2‐hydroxyyunnandaphnine D (**1**) and methyl 7‐hydroxyhomodaphniphyllate (**2**), together with eight known alkaloids, daphnioldhanin D, calyciphylline F, calyciphylline B, deoxycalyciphylline B, daphnicyclidin H, macropodumine C, 9,10‐epoxycalycine
article describes the isolation and structural elucidation of 1 and 2, and their cytotoxicity against HL-60, MCF-7, and A549 cell lines were also evaluated. ## Results and Discussion . -Daphangustifoline A (1) was obtained as an optically active white powder. The molecular formula of 1 was establ