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Two New Alkaloids from Daphniphyllum angustifoliumHutch.

✍ Scribed by Tao He; Ying Zhou; Yue-Hu Wang; Shu-Zhen Mu; Xiao-Jiang Hao

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
237 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

article describes the isolation and structural elucidation of 1 and 2, and their cytotoxicity against HL-60, MCF-7, and A549 cell lines were also evaluated.

Results and Discussion

. -Daphangustifoline A (1) was obtained as an optically active white powder. The molecular formula of 1 was established as C 22 H 29 NO 3 by HR-ESI-MS (m/z 356.2228 ([M þ H] þ ), calc. 356.2225), with nine degrees of unsaturation.

The IR absorption at 1569 cm À1 implied the presence of a COO À anion functionality.

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