✦ LIBER ✦

Two new genome types of adenovirus 7c

✍ Scribed by Jennifer R. Kannemeyer; Louise A. Brooks; K. R. Dumbell; Dr. G. A. Keen

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 458 KB
Volume: 24
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890240113

No coin nor oath required. For personal study only.

✦ Synopsis

Adenovirus type 7 is the type most frequently associated with serious disease. Eighteen different genome types of adenovjrus type 7 had been reported up to October 1986. The genome type Ad7c, based on the restriction enzyme profiles of SmaI and BarnH1, has been reported from Europe prior to 1969 and more recently from South Africa. Here, we report two new genome types of ademvirus 7c !hat have not previously been identified and that have been isolated in South Africa between 1975 afid 1986 from children with postmeasles pneumonia. The two new genome types differ from the prototype Ad7c virus in having two (Ad7ci) or one (Ad7cZf extra cleavage sites for the restriction endonuclease EcoRI. These sites have been located at 3.68kb and 5.32kb from the left terminus of the genome map published for the prototype. Ad7c strain. A strain resembling the prototype Ad7c was also isolated in 1986 from a case of post measles pneumonia.

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