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Two New Cytotoxic Naphthoquinones from Didymocarpus hedyotideus

✍ Scribed by Xi-Bin Xiao; Yue-Xing Lin; Geng-Bo Xu; Xu-Bo Gong; Ying Gu; Jie-Feng Tong; Jing Yang

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
167 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A new naphthoquinone, 6‐hydroxy‐α‐dunnione (1) and a new binaphthoquinone, methyl 1,1′,4,4′‐tetrahydro‐3‐hydroxy‐1,1′,4,4′‐tetraoxo[2,2′‐binaphthalene]‐3′‐carboxylate (2), along with ten known compounds, including naphthoquinones, anthraquinones, and phenylethanoid glucosides, were isolated from the roots of Didymocarpus hedyotideus Chun. Their structures were identified by spectroscopic analyses, particularly 1D‐ and 2D‐NMR spectroscopy. The cytotoxic activities of the two new naphthoquinones were also evaluated.

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