Two new bicyclic ring systems, 1,4,5-benzodioxazocine and 1,4-benzoxazepine
β Scribed by Heino A. Luts
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 433 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3549
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Synthesis of the Novel Thieno[4,3,2-ef ][1,4]benzoxazepine Ring System: 4,5-Dihydro-3-(4-pyridinyl)thieno[4,3,2-ef ][1,4]benzoxazepine Maleate. -The title heterocycle (VI) is synthesized from thiophene (I) by employing an intramolecular nucleophilic aromatic fluoride displacement. Compound (VI) rear
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In a previous paper') we described the generation of o-lithiomethylphenyl isocyanide, which was a versatile reagent for syntheses of indole derivatives. Herein, we wish to report an elaboration of the lithiomethylphenyl isocyanide to lead to heterocycles such as 4,5-dihydro-3,1-benzoxazepine ~~ and