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Two New Acetylenic Derivatives and a New Meroditerpenoid from a Taiwanese Marine Sponge Strongylophora d urissima

✍ Scribed by Shen, Ya-Ching; Prakash, Chaturvedula V. S.


Book ID
126259948
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
41 KB
Volume
63
Category
Article
ISSN
0163-3864

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Jaspines A and B: two new cytotoxic sphi
✍ VΓ©ronique Ledroit; CΓ©cile Debitus; Catherine Lavaud; Georges Massiot πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m