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Two-marker association tests yield new disease associations for coronary artery disease and hypertension

✍ Scribed by Thomas P. Slavin; Tao Feng; Audrey Schnell; Xiaofeng Zhu; Robert C. Elston

Book ID: 106135136
Publisher: Springer
Year: 2011
Tongue: English
Weight: 430 KB
Volume: 130
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-011-1009-6

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Several extensions of the transmission/disequilibrium test (TDT) to multi-allelic markers now exist. In some of these, however, separate tests must be performed on male and female parents because of the non-independence of parental transmission patterns, reducing power, and complicating interpretati