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Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect

✍ Scribed by Bao-Li Chang; Ethan M. Lange; Latchezar Dimitrov; Christopher J. Valis; Elizabeth M. Gillanders; Leslie A. Lange; Kathleen E. Wiley; Sarah D. Isaacs; Fredrik Wiklund; Agnes Baffoe-Bonnie; Carl D Langefeld; S. Lilly Zheng; Mika P. Matikainen; Tarja Ikonen; Henna Fredriksson; Teuvo Tammela; Patrick C. Walsh; Joan E. Bailey-Wilson; Johanna Schleutker; Henrik Gronberg; Kathleen A. Cooney; William B. Isaacs; Edward Suh; Jeffrey M. Trent; Jianfeng Xu

Publisher: Springer
Year: 2005
Tongue: English
Weight: 371 KB
Volume: 118
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-005-0099-4

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## Abstract Genome‐wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat disparate, resulting in multiple, often irreproducible signals becau