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Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12

✍ Scribed by Ethan M. Lange; Lindsey A. Ho; Jennifer L. Beebe-Dimmer; Yunfei Wang; Elizabeth M. Gillanders; Jeffrey M. Trent; Leslie A. Lange; David P. Wood; Kathleen A. Cooney

Publisher: Springer
Year: 2006
Tongue: English
Weight: 325 KB
Volume: 119
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-006-0149-6

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## Abstract Genome‐wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat disparate, resulting in multiple, often irreproducible signals becau