Two Further bis-indole alkaloids from Tabernaemontana bovina
✍ Scribed by Helmut Ripperger; Christine Kamperdick; Günter Adam; Trinh Phuong Lien; Tran Van Sung
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 29 KB
- Volume
- 341
- Category
- Article
- ISSN
- 1615-4150
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## Abstract Two new monoterpene indole alkaloids named ibogamine‐7,8‐dione (**1**) and 12‐methoxyvoachalotine (**2**), and eight known ones, coronaridine (**3**), coronaridine hydroxyindolenine (**4**), 5‐oxocoronaridine (**5**), 3‐oxocoronaridine hydroxyindolenine (**6**), 3‐oxocoronaridine (**7**
An NMR study of two known bis-indole alkaloids is described. In addition to conventional 1D NMR methods, 2D shift-correlated NMR experiments [ 1 Hx 1 H-COSY, 1 Hx 13 C-HMQC-1 J(C,H), 1 Hx 13 C-HMBC-n J(C,H) (n D 2 and 3)] and 2D 1 Hx 1 H-NOESY were used for 1 H and 13 C chemical shift assignments of
## Abstract For Abstract see ChemInform Abstract in Full Text.
This paper reports the separation of the indole alkaloids from the benzene extract of the root barks of Tabernaemontana hilariana (Apocynaceae). The crude alkaloid fraction was fractionated by droplet counter-current chromatography using a low polarity mixture (hexane:ethyl acetate:ethanol:water). N