Two-dimensional Electrophoretic Analysis of Hepatitis-associated Polypeptides in Liver of LEC Rats Developing Spontaneous Hepatitis
โ Scribed by Wirth, Peter J. ;Fujimoto, Yoshinori ;Takahashi, Hidetoshi ;Mori, Michio ;Yoshida, Michihiro C. ;Sugimura, Takashi ;Nagao, Minako
- Book ID
- 108579078
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1990
- Tongue
- English
- Weight
- 657 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0910-5050
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A marked decrease in S-adenosylmethionine (AdoMet) content and a significant decrease in methionine and glutathione contents in the LEC rat liver were observed between the 8th and 12th weeks before start of spontaneous hepatitis. The decreased levels were enhanced by an ethionine or choline-deficien