We report a case of simultaneous diagnosis of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), in which the use of flow cytometry analysis allowed the demonstration of two different cell populations and the study of both immunophenotyping patterns with a large panel of monoclonal
Two color flow cytometric analysis of concomitant acute myeloid leukemia and chronic lymphocytic leukemia
β Scribed by Karen R. Tamul; Dawn C. Meyers; Stuart A. Bentley; James D. Folds
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 522 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0196-4763
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We report on the flow cytometric identification of concomitant acute myeloid leukemia and chronic lymphocytic leukemia in cytology specimens submitted with minimal clinical information. A 64-year-old man presented with fever and progressive dyspnea on exertion. Chest X-ray and computed tomography sc
lmmunophenotyping of peripheral blood lymphocytes from six patients with B-cell chronic lymphocytic leukemia (6-CLL) and five normal volunteers was done and their T and Tn epitopes analyzed using specific monoclonal antibodies and flow cytometry. Lymphocytes from all patients showed strong Tn expres