## BACKGROUND. Extramedullary acute promyelocytic leukemia (APL) is rare, and said to be more common after treatment with all-trans retinoic acid (ATRA) than after any other treatment. ## METHODS. The case of a child with extramedullary relapse of APL after initial treatment with ATRA and that
Two cases of extramedullary acute promyelocytic leukemia
✍ Scribed by Mustafa Benekli; M. Cemil Savaş; Ibrahim C. Haznedaroǧlu; Semra V. Dündar; Mark Weiss; Raymond P. Warrell Jr.
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 214 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0008-543X
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Because extramedullary depositions of APL are uncommon, information concerning the therapeutic Department of Orthopaedics University Ho ˆpital H. Mondor role of ATRA in extramedullary disease is insufficient. In their article, Wiernik et al. state that at least one Creteil, France Gaetano Bacci, M.D
## BACKGROUND. Extramedullary involvement is only occasionally observed in patients with acute promyelocytic leukemia (APL) but has been said to occur more frequently after treatment with all-trans retinoic acid (ATRA) than after treatment with cytotoxic drugs. In the literature, 37 well-documented