## BACKGROUND. Extramedullary acute promyelocytic leukemia (APL) is rare, and said to be more common after treatment with all-trans retinoic acid (ATRA) than after any other treatment. ## METHODS. The case of a child with extramedullary relapse of APL after initial treatment with ATRA and that
Extramedullary acute promyelocytic leukemia
β Scribed by Frederic Maloisel; Jean Emmanuel Kurtz; Francis Oberling
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 47 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. Extramedullary involvement is only occasionally observed in patients with acute promyelocytic leukemia (APL) but has been said to occur more frequently after treatment with all-trans retinoic acid (ATRA) than after treatment with cytotoxic drugs. In the literature, 37 well-documented
Nine children with acute promyelocytic leukemia (APL) are presented. This series of children represents 7% of all acute leukemias and 21% of acute myelogenous leukemias seen during the same period at the Red Cross War Memorial Children's Hospital. These figures are much higher than the incidence quo