Conjugate addition of amines to vinyl su
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Heather Tye
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Article
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2002
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Elsevier Science
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French
β 105 KB
The synthesis of a range of b-amino sulfoximide derivatives is described. The conjugate addition of simple amines or amino acids to N-tosyl phenyl vinyl sulfoximide was achieved in moderate to good yield (41-95%). Electron poor nucleophiles such as tosyl amide or benzyl carbamate were found to be un