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Tumour suppressors: A new role for Dok

✍ Scribed by Skinner, Mhairi

Book ID
109948517
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
223 KB
Volume
10
Category
Article
ISSN
1474-1776

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Two molecular pathways leading to cancer are known. Common-type cancers arise from the 'tumour suppressor' pathway, characterized by gross chromosomal changes and allelic losses (LOH) in an average of 25 per cent or more of randomly chosen chromosomal loci. The 'mutator pathway' has been recognized