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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects

✍ Scribed by Taylor, D D; Gerçel-Taylor, C

Book ID
109998363
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
158 KB
Volume
92
Category
Article
ISSN
0007-0920

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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
✍ Taylor, D D; Gerçel-Taylor, C 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 158 KB

Dendritic and lymphoid ‘exosomes’ regulate immune activation. Tumours release membranous material mimicking these ‘exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived ‘exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv