Tumour cell thrombospondin-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor
β Scribed by Albo, D.
- Book ID
- 111724323
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 126 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0007-0920
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## Abstract There is a strong correlation between the overexpression of urokinaseβtype plasminogen activator receptor (uPAR) and gastric cancer invasion. This study examined the effect of phospholipid lysophosphatidic acid (LPA) on uPAR expression in human gastric cancer AGS cells and the underlyin
## Abstract Plasminogen activator inhibitorβ1 (PAIβ1) binds to the somatomedin B (SMB) domain of vitronectin. It inhibits the adhesion of U937 cells to vitronectin by competing with the urokinase receptor (uPAR; CD87) on these cells for binding to the same domain. Although the inhibitor also blocks