The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
β Scribed by Lamb, Richard F.; Roy, Christian; Diefenbach, Tom J.; Vinters, Harry V.; Johnson, Michael W.; Jay, Daniel G.; Hall, Alan
- Book ID
- 109769468
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 969 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1465-7392
- DOI
- 10.1038/35010550
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## Abstract We investigated the effects of overexpression of the tuberous sclerosisβ1 and β2 (__TSC1/2__) gene products (hamartin and tuberin, respectively) in the human kidney epithelial cell line 293 with an inducible expression system. As we had observed previously in fibroblasts, 293 cells over
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