Tumor–stroma co-evolution in prostate cancer progression and metastasis
✍ Scribed by Sajni Josson; Yasuhiro Matsuoka; Leland W.K. Chung; Haiyen E. Zhau; Ruoxiang Wang
- Book ID
- 116881547
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 637 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1084-9521
No coin nor oath required. For personal study only.
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## Abstract Prostate cancer is a complex disease in which metastasis to the bone is the main cause of death. Initial stages of metastasis are generally similar to those for most solid tumors; however, the mechanisms that underlie the homing of prostate tumor cells to the bone are not completely und
## Abstract Prostate cancer (PCa) epithelial cells require a number of factors to facilitate their establishment and growth at a distant site of metastasis. Their ability to adapt to their microenvironment, proliferate and recruit an underlying stroma is integral to the survival and growth of the m