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279 EPIGENETIC REGULATION IN INHIBITION OF PROSTATE-DERIVED ETS FACTOR, A TUMOR METASTASIS SUPPRESSOR, IN ADVANCED PROSTATE CANCER A TUMOR METASTASIS SUPPRESSOR, IN ADVANCED PROSTATE CANCER

โœ Scribed by Steffan, Joshua; Koul, Sweaty; Meacham, Randall B.; Koul, Hari


Book ID
118483081
Publisher
Lippincott Williams and Wilkins
Year
2011
Tongue
English
Weight
39 KB
Volume
185
Category
Article
ISSN
0022-5347

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The KAI1 gene, isolated from human chromosome 11p11.2, has been implicated as a prostate cancer metastasis suppressor gene. Recent studies have demonstrated that the expression of KAI1 protein is reduced in metastases of human prostate cancers and is inversely correlated with tumour grade. The objec