Carcinogenicity of Glycidol in F344 Rats
โ
Richard D. Irwin; Scot L. Eustis; Steven Stefanski; Joseph K. Haseman
๐
Article
๐
1996
๐
John Wiley and Sons
๐
English
โ 740 KB
Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr